Monday, August 23, 2010

Have you ever heard of....................?

have you ever heard of the skin condition "knuckle pads"


do you know anyone with this disorder????


any knowledge would be appreciated.


thanks....

Have you ever heard of....................?
Yes, I work in dermatology and have for about 10 years and here is some info for you it is also known as PRURIGO NODULARIS, we treat it with topical steriods and sometimes a cortisone injection depending on how bothersome it is for you.





Most knuckle pads are idiopathic or are related to repetitive trauma. Work-related trauma with repeated motions or rubbing of the PIP joints or knuckles, as seen in live-chicken hangers in a poultry processing plant, has been reported. Athletes, such as boxers, have been known to traumatize their knuckles and fingers in a repetitive fashion, causing knuckle pads. Surfers have developed "surfer's knots" from repeated friction between the surfboard and the body part exposed to the repeated trauma. A few cases involving the toes have been reported; these cases were thought to be sequelae of ill-fitting shoes. Also known in people who suffer from bulimia from constantly putting their fingers down their throats and their knuckles scraping their teeth.





Psychologically disturbed children who bite and suck their fingers cause thickenings that resemble knuckle pads to occur in the skin in the traumatized areas. Patients with bulimia who use their knuckles or fingers to induce emesis sometimes develop fibrotic papules resembling knuckle pads.





Some cases of knuckle pads are familial. They have been associated with the autosomal dominant palmoplantar keratoderma with and without ichthyosis vulgaris. Knuckle pads were found in 2 families with autosomal dominant sensorineural deafness and leukonychia (Bart-Pumphrey syndrome). Knuckle pads also have been reported in pseudoxanthoma elasticum. Dupuytren and Peyronie diseases and Ledderhose disease are at times observed together, and the triad may be associated with knuckle pads. Knuckle pads also have been associated with esophageal cancer, hyperkeratosis, and oral leukoplakia. One case report links phenytoin with polyfibromatous syndrome.


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